Meanwhile Everton will be without Seamus Coleman, James McCarthy, Ramiro Funes Mori and Morgan Schneiderlin, with Coleman suffering a horrific double fracture to his leg playing for the Republic of Ireland against Wales.
Centre-back Funes Mori has played 23 Premier League matches this season, with the blow coming at a crucial time in Everton's season.
Funes Mori's injury comes after starting right-back Coleman suffered a double leg fracture while playing for Republic of Ireland against Wales during the same global break.
"He will have a surgical opinion next week but the initial diagnosis suggests the 26-year-old is likely to be out of action for the rest of the campaign", his club said in a statement.
LeBron, Cavs end rough March with 122-105 win over 76ers
Lue already took some heat these last couple of weeks on resting James, Irving, and Love in order to prepare for the playoffs. However, heading into that game, they're going to be in an awkward position with some conflicts of interest.
"As everyone knows, when teams do sit in against Liverpool, it normally causes Jurgen Klopp's side problems, but I don't think Koeman is the type of manager who will try it".
Adam Lallana has also been ruled out with the thigh injury he suffered on worldwide duty for England while Sturridge, who was pictured back in training this week, is only still working with the fitness coaches following a hip injury and is not in contention.
The club announced the news on Thursday morning and he will now undergo surgery on his knee in an attempt to make sure a full recovery is achieved.
There's better new for Chelsea with Belgian internationals Eden Hazard (calf) and Thibaut Courtois (hip) returning to training ahead of the clash with Crystal Palace. Sunday: Southampton v Bournemouth 2.30am; Swansea City v Middlesbrough 10.30pm.