Hours later, a Vasquez-Oliva - believed to be the woman's husband, and the father of the two children - was found almost 100 miles away in San Francisco.
He's been booked for homicide and is in custody at the Sacramento County Main Jail.
Police say a man suspected in the killings of two adults and two juveniles in Sacramento has been arrested.
Salvador Vasquez-Oliva was arrested early Friday in connection with the murders..
At this time the names, sex, gender, and relationship of the victims are not being released to the public and will be completed by the Coroner's Office at a later time, police said.
Neighbor Rita Munoz told the Sacramento Bee that a couple with children ages 11 and 14 live in the house.
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On Thursday, detectives were in the Bay Area - San Francisco and San Pablo - to question a person of interest and investigate other leads.
Sacramento Mayor Darrell Steinberg said that at least two of the victims were children.
The woman was going through a "very hard divorce" according to a relative who spoke to NBC.
Don Sherrill, whose Lundy Court house shares a backyard with the taped-off home, said he remembered talking to a man and his two children - a boy and a girl - a few years ago after burglars struck the 35th Avenue home. Police also weren't saying how they were killed. A basketball hoop sat in the middle of the home's driveway.
There were no reports of shots fired or other problems until the relative called to report that he was concerned about the welfare of the home's residents, Sacramento police spokesman Sgt. Bryce Heinlein said. All our hearts here at City hall go out to the victims, their families, schools and community. "And as a city we stand ready to embrace the families and the communities in any way we can to help". Upon entering, officers found the four victims dead inside.
Traffic around the 1100 block of the avenue is expected to be impacted for the remainder of the day as police work on the suspected homicide investigation.