Other than those two absentees, however, Ronald Koeman has an nearly fully fit squad to choose from as the Toffees look to close the gap on the top seven. While Lukaku is banging in the goals for Everton at the moment, Kane is starring for Tottenham Hotspur yet again this season. "Like I always told you it's a business I know very well", the Argentine added.
It was a surprise admission from Pochettino given Kane is one of the most amiable friendly players at Tottenham but it was an illustration of his commitment and drive to become the best player he can.
His ability to take chances has made him one of the most prized assets in the Premier League, but the Walthamstow-born man will be making his side aware that with the visit of Everton this Sunday brings another free-scoring striker in the shape of Lukaku.
If Spurs were to win here, they would set a new home Premier League club record for successive wins at White Hart Lane (9).
"I want to explain that Harry has a very good character, he is very strong, very professional".
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"To compare is too hard", Pochettino said.
And Kane, who believes becoming a first team regular enhances a player's connection with the fans, stated that he is certain about his bond with the supporters being intact for the entirety of his career.
The 23-year-old Londoner, who has netted 17 times in the Premier League this term, is joint-top of the goalscoring rankings alongside Arsenal's Alexis Sanchez and Everton's Romelu Lukaku. If you ask Koeman, Lukaku is the best.
There will be goals as both teams are excellent going forward and the defences will not be able to live with the attacking quality both sides have.